姓名：杨胜彩
职称：副教授
最高学位：博士
邮箱：yang_shengcai@jlu.edu.cn
电话：18744015976
工作地点：生命科学楼236室
研究方向：酶分子组装与递送研究、肿瘤与炎症基因治疗研究
教育经历：
2010.09-2014.07 公司化学学院 化学 学士
2014.09-2019.07 公司化学学院 高分子化学与物理 博士
2014.09-2019.07 中国科学经理春应用化学研究所 高分子化学与物理 博士（联合培养）
工作经历：
2019.09-2022.03 新加坡生物工程与生物影像研究所，新加坡科技研究局 博士后
2022.06—至今 公司分子酶学工程教育部重点实验室 副教授
荣誉奖励：
2022年，入选公司“唐敖庆青年学者“支持
研究成果：
1. Shengcai Yang, Zhaohui Tang*, Chenyang Hu, Dawei Zhang, Na Shen, Haiyang Yu, Xuesi Chen*. “Selectively potentiating hypoxia levels by combretastatin A4 nanomedicine: Towards highly enhanced hypoxia-activated prodrug tirapazamine therapy for metastatic tumors” Adv. Mater., 2019, 31, 1805955. (IF：32.086)
2. Shengcai Yang, Jiayu Leong, Yanming Wang, Rachel Sim, Ko Hui Tan, Yau Hong Chua, Nathanael Tan, Ashlynn LZ Lee, Joyce Tay, Yi Yan Yang*. “Drug-free neutrally charged polypeptide nanoparticles as anticancer agents” J. Control. Release, 2022, 345, 464-474. (IF: 11.467)
3. Shengcai Yang, Yanming Wang, Jason Tan, Jye Yng Teo, Ko Hui Tan, Yi Yan Yang*. “Antimicrobial polypeptides capable of membrane translocation for treatment of MRSA wound infection in vivo” Adv. Healthc. Mater. 2022, 11 (6), 2101770. (IF: 11.092)
4. Shengcai Yang, Zhaohui Tang*, Dawei Zhang, Mingxiao Deng, Xuesi Chen. “pH and redox dual-sensitive polysaccharide nanoparticles for the efficient delivery of doxorubicin” Biomater. Sci., 2017, 5, 2169-2178. （IF：7.590）
5. Shengcai Yang, Dawei Zhang, Na Shen, Guanyi Wang, Zhaohui Tang*, Xuesi Chen. “Dihydroartemisinin increases gemcitabine therapeutic efficacy in ovarian cancer by inducing reactive oxygen species” J. Cell. Biochem., 2019, 120, 634-644. （IF：4.480）
6. Shengcai Yang, Na Shen, Wantong Song, Zhaohui Tang*, Xuesi Chen*. “A novel monomethylauristatin E prodrug for malignant cancer targeted therapy” J. Controlled Release 2017, 259, e120. （IF：11.467）
7. Xinghui Si, Wantong Song*, Shengcai Yang, Lili Ma, Chenguang Yang, Zhaohui Tang*. “Glucose and pH Dual‐Responsive Nanogels for Efficient Protein Delivery” Macromol. Biosci. 2019, 19, 1900148. （IF：5.859）
8. Jiayu Leong, Danrong Shi, Jeremy Pang Kern Tan, Chuan Yang, Shengcai Yang, Yanming Wang, Yeen Shian Ngow, Jessica Kng, Nithiyaa Balakrishnan, Shu Qin Peng, Chun Siang Yeow, Balamurugan Periaswamy, Shrinivas Venkataraman, Andrea Lay‐Hoon Kwa, Xiaoli Liu, Hangping Yao, Yi Yan Yang, “Potent antiviral and antimicrobial polymers as safe and effective disinfectants for the prevention of infections” Adv. Healthc. Mater. 2022, 11 (9), 2101898. (IF: 11.092)
9. Na Shen, Jing Wu, Chenguang Yang, Haiyang Yu, Shengcai Yang, Tete Li, Jingtao Chen*, Zhaohui Tang*, and Xuesi Chen*. “Combretastatin A4 nanoparticles combined with hypoxia-sensitive imiquimod: a new paradigm for the modulation of host immunological responses during cancer treatment” Nano Lett., 2019, 19, 11, 8021-8031. （IF：12.262）
10. Guanyi Wang, Dawei Zhang, Shengcai Yang, Yalin Wang, Zhaohui Tang*, Xueqi Fu* “Co-administration of genistein with doxorubicin-loaded polypeptide nanoparticles weakens the metastasis of malignant prostate cancer by amplifying oxidative damage” Biomater. Sci., 2018, 6, 827-835. （IF：7.590）
11. Chenyang Hu, Ranlong Duan, Shengcai Yang, Xuan Pang*, Xuesi Chen*. “CO2 controlled catalysis: Switchable homopolymerization and copolymerization” Macromolecules, 2018, 51, 4699-4704. （IF：6.057）
